Aged T Cells Secret Granzyme K, Driving Cognitive Decline
New research reveals how aged immune cells, specifically CD8+ T cells, secrete Granzyme K, contributing to cognitive decline in a reversible way.
New research reveals how aged immune cells, specifically CD8+ T cells, secrete Granzyme K, contributing to cognitive decline in a reversible way.
Biological aging clocks are evolving beyond chronological age. Explore how multi-omics approaches are creating more precise tools for understanding health, disease, and longevity.
Explore how public health, clinical medicine, and geroscience must integrate to tackle chronic age-related diseases and extend healthy human lifespans.
Discover how PM20D1 and N-oleoyl-leucine may boost microglia’s ability to clear amyloid-beta in the brain, offering a novel strategy for Alzheimer’s disease research.
New research reveals how senescent cells in dental pulp contribute to tooth aging, making teeth brittle. Senolytic therapies show promise in restoring dental health.
Explore the Hallmarks of Aging, a pivotal framework that has unified and propelled geroscience, guiding research and therapeutic development.
Harvard Health Publishing’s ‘Pathways to Longevity’ report signals a new era for aging science. Explore key concepts, emerging therapies, and lifestyle foundations for a longer, healthier life.